I just trimmed my guys’ nails for the first time a couple of days ago, they’re about 10 weeks and 15 weeks old. Those are some seriously tiny little nails, and I have some seriously awful eyes, so it was about as fun as it sounds. I tend to do my nail clips about every month, though I will keep an eye on things and if I think it’s needed I’ll do them earlier/later than that.
What I do for nail trims is, I sit on the floor and I prop my legs up and together in front of me. I gently lower the rabbit onto their back in the little groove between both legs and try to trim as many nails as I can until they start to wiggle. I usually get about a foot or two done, then rearrange them as needed (though there may be an escape or two for the first time!). For the first nail clips I don’t really worry about cutting them to the correct length, I just make sure to snip off the sharpened ends if I’m not quite sure how long they are. I’d rather the whole thing go off smoothly and them having a touch too long of nails than to make the first few times a painful experience.
Though I will admit that my way of doing it does take a bit more experience in holding animals, if you’re not sure or are nervous about hurting them, the bunny burrito may be the way to go.