I have no direct experience, but generally I’ve heard the best approach is to stop for food/water breaks, rather than putting that stuff in their pens with them. Those require dishes and somewhat solid objects, which can fling against or knock into your rabbits at a moments notice from a too-hasty stop. I suggest taking a cooler to have water bottles and hay/veggies, then taking pit stops where you take the time to present food and water to each bun before hitting the road again.
The humane society website states: “Longer car trips create more challenges. Rabbits must eat hay and drink water frequently to keep their digestive systems moving. Most rabbits won’t eat or drink in transit, so you’ll need to stop at least every two hours to give them an opportunity to relax, eat, and drink.”
Wick’s been on 1.5hr car rides, and we just make sure he eats, pees, and poops before getting into his carrier. I lay a pee pad down because he can’t hold his pees that long, and its been quite successful.
The answers provided in this discussion are for general guideline purposes only. The information is not intended to diagnose or treat your pet. Seek the advice of your veterinarian or a qualified behaviorist.