If he’s wheezy, I’d suspect an infection rather than e cuniculi. The nose and mouth and ears are connected via the ear-trumpet (the Eustachian tube). Bacteria can move freely between those structures.
Most, perhaps even all, rabbits have pasteurella bacteria in their nasal cavities. Not all rabbits get sick from those bacteria, but some do, for reasons still not known. The bunny gets a “bunny cold” aka “the snuffles”. Typical symptoms can be wheeziness, thick white mucus from the nose and/or an ear-infection.
Imo you should call your vet first thing on Monday so you can get proper meds for your bun. Baytril is first-choice antibiotics. There are also decongestants suitable for rabbits. Your vet will probably prescribe a week-long course of Baytril for starters, but the rabbit often needs to be treated for several weeks. The sooner you start treatment, the better the prognosis of course.