It is possible that the antibiotic isn’t sitting well with your rabbit. I would call the vet to update them on your observations. Your vet may recommend skipping the next dose and coming in again.

If your rabbit has a sensitive stomach, it may be worth asking your vet to do the treatment through shots, rather than an oral medication. I’ve heard that helps.

Wick has taken a lot of oral antibiotics, and the only one he could not tolerate (stomach pain after a dose; gurgly stomach) was flagyl, which is a safe medication, but didn’t sit well with Wick. I called the vet and they advised to skip the next dose, see if the gastric distress still occurs, and come in for a visit. At the visit, we decided to go to just Flocillin shots to treat Wick’s tooth infection at the time, instead of the oral flagyl.

I’m unsure if rhinitis is the same, a subset, or an umbrella term which includes upper respiratory infections, but Wick had a URI when I got him. I can’t picture yellow spots or what they’d have to do with a nasal condition, but if your vet is knowledgeable, it’s good you have a diagnosis! From my experiences with Wick, I know there are many types of antibiotics and some have different side effects on different bunnies, so I think discussing with your vet your rabbit’s reaction is a good first step to revising treatment.

Wishing you and your rabbit the best!