welcome here!
i think only you can really make that call. the car will stress out a bunny, but so will being in a strange environment. i know folks have traveled by car with their bun and everything is fine. keep in mind that you will need to bring a lot of stuff with you, towels to refresh the bottom of the carrier, food, hay, water from home, a pen to stay in when you get where you’re going. you will need to make frequent stops b/c not all buns will eat in a moving car, so i would say about every 1.5 or 2 hours, you might have to stop for a half hour. another thing to consider is temperature. bunnies overheat very easily at ovr 80 degrees. so the car might be toasty for you, but it may be too hot for your bunny. also, consider what the environment is like where you’re going? are there dogs, loud children, a lot of hustle and bustle (very possible since it’s a holiday!)
boarding has it’s own inconveniences, strange location, unfamiliar smells, price tag.
i think the ideal is if you can have someone come to your home, petsitter, or even a friend or neighbor… but agian that might be harder over the thanksgiving holiday…
i know Osprey has a lot of experience in car travel with bunnies, so hopefully he can stop by and offer some more advice (or correct me… lol!)