I don’t use tiles for my primary flooring, but I do currently use laminate “hardwood” planks with cotton towels and love the set-up, and they act sort of similarly to tile. I often have Theodore out in the hallway for a few hours of exercise, and that is tiled. If your buns are fine with smooth flooring, tile is kind of an awesome substrate because it’s super easy to clean, retains cold so the buns can lay down and absorb the coolness during hot days, and they can’t chew it up! The one thing that can be an issue is if they decide to do Bunny 500s or binkies on tile, they can slip as there’s no traction. But, if they’re safely enclosed, that shouldn’t result in anything too bad.
The one thing that I think is key in any habitat of course is to provide a variation of flooring. That is to say, you will likely want to provide cotton towels and/or seagrass mats and/or cardboard, etc. just so that they have something a bit softer to hang out on if they want to. If your bunnies are comfortable on slippery flooring, I’d say definitely go for it!