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The subject of intentional breeding or meat rabbits is prohibited. The answers provided on this board are for general guideline purposes only. The information is not intended to diagnose or treat your pet.  It is your responsibility to assess the information being given and seek professional advice/second opinion from your veterinarian and/or qualified behaviorist.

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Forum DIET & CARE Known problems with Xeno 450

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    • judyandhoney
      Participant
      3 posts Send Private Message

        Hi all,

        One of my rabbits has recently died, around 18 hours after treatment with Xeno 450 (spot
        on treatment of Ivermectin by Genitrix). Both rabbits have been treated for mites at the same time, both came home within 5-10 minutes, started grooming themselves and each other, spreading the fluid to their bodies, head and ear, and no doubt ingesting the medication. The same evening, both rabbits seemed quiet and didn’t want to eat anything. In the morning i got up to find one rabbit extremely bloated and cold, died at the vets a few hours later.

        The treatment with Xeno 450 may or may not be linked to my rabbits death, but I am trying to find any information of known effects/side effects/allergic reactions after treatment with Xeno 450 so that I can pass to manufacturer. Genitrix are not aware of any side effects of the medication (even if ingested) but are willing to consider any cases  I can present. Has anybody ever had or heard of anything worth reporting? Does anyone have any information with regards to white rabbits being more susceptible to any side effects? 

        Thank you for your help… I hope that, if there is a problem, it can be identified… and I hope it helps other bunnies…
         


      • Sarita
        Participant
        18851 posts Send Private Message

          Did you have your vet do a necropsy? I’m not familiar with this treatment. I do know that ivermectin is safe.


        • judyandhoney
          Participant
          3 posts Send Private Message

            No, I was in shock for many days, my vet never offered a necropsy… shame because I would have given the go ahead. Proper procedures have not been followed with Genitrix either when reporting the death. Because no forms have been filled in, Genitrix never asked for the body.


          • Sarita
            Participant
            18851 posts Send Private Message

              Oh that’s too bad. I do think a necropsy would have been helpful. At least then you may have known something although necropsy’s are not always conclusive which doesn’t help if you are trying to find closure. But it may have shown something that the vet could share with the company and share with you.

              I understand your shock and I’m sad for your loss.

              Did you just give this to one rabbit? How is your other rabbit doing?


            • judyandhoney
              Participant
              3 posts Send Private Message

                Both rabbits fell unwell afterwards, both rabbits stopped eating… One died the next day from extreme bloat… My other rabbit was later treated with Ivomectin injections to clear the mites, she now only suffers from the loss of her friend…


              • Sarita
                Participant
                18851 posts Send Private Message

                  Did your vet recommend this treatment? I did look this up and it does say it’s made especially for rabbits, etc…

                  It is possible that it is totally unrelated and giving the treatment was just a coincidence. Hopefully you will find some other members who have used this treatment.


                • Deleted User
                  Participant
                  22064 posts Send Private Message

                    Ivermectin can kill a rabbit, even if the product containing it is formulated for that species. There are always indivuduals with higher sensitivities. Ivermectin, like many parasite medications, attacks the nervous system. I am so sorry that this happened. Even if it cannot be determined what the cause for your rabbits’ death was, I would let Genitrix know what occured.


                  • RabbitPam
                    Moderator
                    11002 posts Send Private Message

                      I’m very sorry for your loss. It sounds like it was terrible for both your bunnies.
                      I’m not sure I would blame it on that particular medicine though. At least not inherently with the meds, but rather with how it interacted with the bunny who died. Since the other one was bothered but survived, unless there was a significant difference in their dosages, it doesn’t sound like it was a bad batch or they both would have passed. It’s also possible that there was more wrong with the one bunny, and it was all too much for him. I also was going to ask if you could get a necropsy, but agree you can report it to Genitrix just to see if they are watching for any bad reactions.

                      Bunnies are so delicate in many ways. I’m sending pets to your other bunny to make a full recovery from her illness, treatment, and loss of her friend.


                    • bunnytowne
                      Participant
                      7537 posts Send Private Message

                        OH nooo thats so sad.

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                    Forum DIET & CARE Known problems with Xeno 450