What is her diet like? Perhaps it’s something she is eating that is causing the distress.

I would suspect a dental problem.  As you say, they molars can often not be properly seen unless the bun is sedated, although a good rabbit vet can often get an idea by looking with an otoscope when the bun is burritoed. Dental x-rays are the only way to see  the tooth roots.  Overgrown teeth are a very common thing with rabbits.

I have a dental bun who took a very long time to recover from stasis last fall, more than a month. It was exhausting! My bun typically seemed to feel better late in the evening, he too got metacam twice per day.

We have another member whose bun didn’t tolerate cisapride. It is a drug which isn’t used very much these days. You could perhaps ask your vet to try metaclopramide (Reglan) instead?

Gas will always occur in the bunny gut when there’s an eating-problem. To help with gas you can give simethicone baby gas drops. Some vets say gas drops won’t help because a bun can’t burp, but buns absolutely can fart. Gas is painful for rabbits. She may feel more of that in the mornings, after a night of physical rest. Body movement (physical “exercise”) helps the intestines move so gas and poop can come out, there could perhaps be some gas build-up that happen overnight.

My bun (2 years old, male) is currently in recovery, according to our vet, even though he has these recurring GI symptoms for about 6 weeks already. He is very energetic at night, he shows no sign of pain or stress, but he just refused to eat and rarely drinks, and really inactive in the daytime. It breaks my heart that I need to force-feed him every day. My other rabbits were all on the same diet, and they never have this problem before. (The diet is 1/4 cup of pellets, 2 cups of veggies per day, unlimited hay and water). At the moment I only offer him hay and water, to make sure pellets and veggies not causing this.

I already took him to 2 vets, full-body check-up, x-ray, and CT scan. There was no obstruction, problematic gas, his GI tract seems to work normally, and the vets couldn’t find anything wrong with him. Then, again he just doesn’t eat or drink enough.

During these 6 weeks, my bun condition has been going up and down. On week 4, he seems to start eating normally, and then at week 5, he stopped eating again. I do hope your bunny recover in a mere day or second because I do feel your stress and anxiety. Even, my bun still not fully recover, but he still here and seems to be happy. So, I would like to encourage you to don’t lose hope and keep going. Some bunnies are born with this chronic health problem, which is unlucky for the bun and the caring owner. But just do your best, and know that your bun is not alone in this fight. If your vet rules out a GI problem, maybe ask for a dental check, blood work, or urinary analysis. I hope you find the root of the problem soon.