I just adopted a bunny who was neutered a week ago. He was totally litter trained in his foster home but was peeing and pooping all over the place at my house. I’m also hoping it’s hormones. I’ve been crating him and slowly letting him out for 5-15 minute intervals a few times a day in increasingly large spaces. He’s using his litter box perfectly in his crate and fingers crossed has done well with those intervals. Keep us posted.