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› FORUM › DIET & CARE › GI Stasis Recovery
Hi, I have a two year old dwarf hotot bunny we adopted last year named Watson. Since Monday, he has not been popping or acting his usual energetic self. He was plopping on his stomach, not wanting to be held, and fidgeting in his bed area all night. With no 24 hour vet nearby I gave him some infant gas drops we had leftover from some gas he had over Christmas (it wasn’t severe and passed within a few hours) and some Critical Care because he had been refusing food all day.
We immediately took him to the vet on Monday morning and he was diagnosed with GI Stasis. Initially, he was prescribed with Metoclopramide, Metacam and Sulfatrim. After little changed in the next day, I took him back on Tuesday and the vet said to start introducing a little pineapple juice into his critical care to encourage him to fidget less when he’s syringe fed. Our vet noted that she was able to hear noises in his stomach which was a good sign and acting very alert even peeing on the table.
We spent most of Thursday thinking the worst of it was over because he pooped a very small pellet, was taking his critical care and medication without issue, was drinking out of a bowl if we left it next to where he was laying and peeing frequently (he still is). However, this morning after giving him his medicine he didn’t pass anything (previously, after getting his medicine he would pass some mushy poop or mucus) and after feeding him he started to grind his teeth very loudly and was acting extremely lethargic so we rushed him to the vet. She noted that his stomach had felt more tense than the previous two visits so she recommended an x-ray. The x-ray showed a lot of gas in his lower gastric tract, but no problems with his teeth, organs, or solid blockage in his system. The vet noted he was well hydrated and fed and hasn’t lost any weight, but prescribed Cisapride and upped the dosage of his Metoclopramide to target the amount of gas.
At the moment he’s being monitored 24/7 by someone and we’re trying to rub his tummy when we can tell he’s in a lot of discomfort. I’m wondering if anyone on this forum can provide any information on the medication we have and what his recovery might look like, additionally, does his condition sound at all like it could be potentially fatal? A lot of the cases of fatal GI Stasis I’ve found online had do to with enlarged hearts, organ failure, dehydration, etc. My family is all very nervous about his recovery and want to make sure he’s being treated as comfortably and carefully as possible, so any advice, stories or words of encouragement to alleviate our anxiety would be greatly appreciated!
A small update, about 2 hours after taking his Cisaprode and Metoclopramide he’s shaking a little. I know these are both supposed to help the gut move, so is the discomfort normal? He’s drank a little out of a bowl after taking his medicine and I’m about to feed him some more critical care soon.
Sorry for the bump but we’re on day 5 of stasis with no pooping (aside from a single small drop and some mucus the first two days) and he’s been grinding his teeth a lot since getting his medication/critical care this morning. I called the vet and she didn’t think seeing him today was necessary and that the best we could do right now was keeping him hydrated and fed because Cisaprode/Metoclopramide is going to force his gut to move. It’s very hard hearing his teeth grinding so much!
Has anyone had bouts of stasis that’s lasted this long?
I’m sorry you’re gonna through this. I had a bun who passed to this a while back. I always say this, never give gut motility drugs before an X-ray as a blockage in an intestine could be ruptured from the meds. And X-rays can’t always show a blockage( my one had a blockage that an X-ray couldn’t show).
Metaclopromode and cisapride are amazing drugs but can cause very intensive mussel cramping pains when used together. Mine was on it for 12 hours and had to take him off metaclopromide since it was too much with cisapride. Sometimes 2 is worse than just one drug. Are you syringe feeding him pure water? He might be dried up somewhere along the gi tract and direct moisture to that area can help soften things up. And you’re doing the four feedings that critical care says to do? Have you been able to see a different rabbit savvy vet for this?
This is an emergency that needs to be seen and I’m sorry no one responded earlier. Ask the vet if you can discontinue one of the gut motility drugs. You can stretch the stomach muscles enough to where the receptors can’t talk with eachother to tell them to empty the stomach if too much food has been given.
Did you take pictures of the X-ray you could post on here? Did she say she saw poops on it and they were just stuck?did the intestines have any poop in them or was the only thing full the stomach? This seems to me to be a blockage in the cecum since it isn’t showing up on an X-ray. Are you able to get another X-ray now and see if anything has moved along his gi tract?
He seems to be in much more pain than he should. See if the vet can switch metcam to buprenorphine, it’s a great painkiller, it can make them lethargic but it helps ease their pain and allow them to calm down to try and get things moving again. As metacam is just an anti inflammatory and not a pain killer.
I don’t want to scare you, but my bun had stasis on and off for 5 months and then the last bout he had, it was for a week and X-rays didn’t show anything. Ended up he had a blockage in his cecum.
Posted By Bunny House on 1/19/2019 1:41 PM
I’m sorry you’re gonna through this. I had a bun who passed to this a while back. I always say this, never give gut motility drugs before an X-ray as a blockage in an intestine could be ruptured from the meds. And X-rays can’t always show a blockage( my one had a blockage that an X-ray couldn’t show).Metaclopromode and cisapride are amazing drugs but can cause very intensive mussel cramping pains when used together. Mine was on it for 12 hours and had to take him off metaclopromide since it was too much with cisapride. Sometimes 2 is worse than just one drug. Are you syringe feeding him pure water? He might be dried up somewhere along the gi tract and direct moisture to that area can help soften things up. And you’re doing the four feedings that critical care says to do? Have you been able to see a different rabbit savvy vet for this?
This is an emergency that needs to be seen and I’m sorry no one responded earlier. Ask the vet if you can discontinue one of the gut motility drugs. You can stretch the stomach muscles enough to where the receptors can’t talk with eachother to tell them to empty the stomach if too much food has been given.
Did you take pictures of the X-ray you could post on here? Did she say she saw poops on it and they were just stuck?did the intestines have any poop in them or was the only thing full the stomach? This seems to me to be a blockage in the cecum since it isn’t showing up on an X-ray. Are you able to get another X-ray now and see if anything has moved along his gi tract?
He seems to be in much more pain than he should. See if the vet can switch metcam to buprenorphine, it’s a great painkiller, it can make them lethargic but it helps ease their pain and allow them to calm down to try and get things moving again. As metacam is just an anti inflammatory and not a pain killer.
I don’t want to scare you, but my bun had stasis on and off for 5 months and then the last bout he had, it was for a week and X-rays didn’t show anything. Ended up he had a blockage in his cecum.
Thank you so much for your response!
Unfortunately I do not have a copy of his x-ray. They took two x-rays of his side and bottom and it showed no blockage but just gas in his lower gastric tract and some in his upper. Our vet specializes in hamsters, gerbils and rabbits so I’ve felt comfortable in our relationship we’ve had since he was neutered around 9 months ago. He’s been drinking well on his own (last night I gave him a bowl of water and this morning it was almost completely gone with no spillage around his pad). He’s peeing frequently and his butt looks brown and sticky like he had runny poops (though on his pad this morning it was only rust colored urine). Our vet has closed for the weekend (it closes at 3 PM) so I won’t be able to call and ask until Monday morning.
I’ve been giving him about 6 ML of critical care mixed with water and a splash of pineapple juice every 3 1/2 – 4 hours and he’s taken it relatively well, though today with the introduction of Cisaprode he’s been acting less mobile, but still alert.
When I spoke to the vet earlier this morning she said that his pain was going to be normal given the two drugs he’s on.
At the moment Watson is sitting in my lap and when I rub his tummy I can hear gurgling noises, which my vet told me was a good sign.
I’m so sorry your bunny passed from this. Had the blockage in the cecum been caught sooner would their have been a treatment route?
Okay. Then keep doing what you’re doing and hopefully he gets better.
We did all we could and with a blockage, you can’t really do anything. Since he wasn’t getting better we had an exploratory done and the vet removed hair and poop from his cecum but unfortunately with gi surgery in buns, the mortality rate is about 95% so he passed right after waking up. That’s why it’s so important to do oral fluids Incase subq fluids aren’t getting to the gi tract.
I just gave him his medicine again and he’s acting very sluggish and not moving as much as he’s used too, so I’m doing my best to encourage him to move and get him out of his cage. Still feeding him water and critical care at the same times. He’s not drinking out of a bowl now and I noticed he hasn’t peed in a few hours so I’ve syringe fed him water to keep him hydrated.
He made this runny poop-like material earlier today and I attached the image because it I don’t think its urine and I’m wondering if this is a good sign? He has some of sticky substance around his butt. Very nervous about tomorrow because I won’t have any access to a vet and our normal vet isn’t working on Monday (though we will still likely bring him in to see someone and ask about his cecum, our vet was pretty confident it wasn’t anything physically blocking him except for the gas, she said she had seen cases worse than this with the amount of gas).

I’ll keep posting updates throughout the week. Thanks to Bunny House and anyone else taking the time to read/respond in advance!
Is there a picture you can upload of his butt? Is the sticky substance colored and does it smell?
If you say its not pee, then that has to be pure diarrhea and that is very bad for a bun, that means a bacterial infection of the gi tract. Does the brown liquid have a smell?
I would try and syringe feed him 100 ml of water to try and keep him hydrated. have you taken his temperature?
Has he pooped any clear jelly out yet? It would mean his GI tract is starting back up and an indicator of a inflamed gi tract.
Posted By Bunny House on 1/19/2019 6:10 PM
Is there a picture you can upload of his butt? Is the sticky substance colored and does it smell?
If you say its not pee, then that has to be pure diarrhea and that is very bad for a bun, that means a bacterial infection of the gi tract. Does the brown liquid have a smell?
I would try and syringe feed him 100 ml of water to try and keep him hydrated. have you taken his temperature?
Has he pooped any clear jelly out yet? It would mean his GI tract is starting back up and an indicator of a inflamed gi tract.
The liquid does have a smell, somewhat similar to urine. I’ve been syringe feeding him water throughout the day. If he does have a bacterial infection in his GI tract is that treatable?
He has not pooped any clear jelly since the first day of his stasis.
Hi there, sorry your bun is poorly
Just catching up on this, and skimmed, so sorry if I missed something that’s been covered!
It can take different combinations of motility meds, depending on where the slow-down is. Ciscipride works mainly on the upper GI, and metaclopromide/reglan works on the lower, so a combo of the two can be needed. I’m guessing since the vet saw the build up of gas in both areas, both regions might be slowing. The cramping can be very painful so the pain meds are very important.
Loud gurgling can be gas, which can be very painful, so keep up with his pain meds and tummy rubs. You can also try massaging along his spine, which stimulates the gi tract (or so I’ve been told… and I’ve found it seemed to help poorly buns before). I’ve noticed with my buns that they did better with splitting the metacam into smaller more frequent doses rather than a larger less frequent dose. Do you notice he does better right after his pain med dose?
It is concerning that there are still not poops after such a long course of motility meds, but restarting a gut that’s in full stasis can be like “jump starting a train”, so try not to lose hope, and stick with the treatment as much as possible. It can take several days for poops to return.
Antibiotics can help, they can make things worse. If he does have an infection in his GI the vet can prescribe an antibiotic for that. I agree with BH that it is important to figure out if the brown is from urine, mucous, or poop… and true watery diarrhea is a medical emergency for buns.
Taking his temperature regularly is a good idea, as pain can cause rabbit’s temp to fluctuate and send them into shock. If that happens they end up with a low temp, and it’s important to keep him warm. You can provide a warm bottle wrapped in a towel for him to cuddle up to, or just hold him on your lap and use your body heat.
I hope he improves soon!
((((Vibes for Watson))))
. . . The answers provided in this discussion are for general guideline purposes only. The information is not intended to diagnose or treat your pet. Seek the advice of your veterinarian or a qualified behaviorist.
This article shows what true diarrhea looks like: http://www.medirabbit.com/EN/GI_diseases/drop/Drp_en.htm
I also found this on ciscapride:
http://www.medirabbit.com/Safe_medication/GI_stimulation/cisapride.htm
I wonder if he might be reacting negatively to it?
Here’s some info on metaclopromide:
http://www.medirabbit.com/Safe_medication/GI_stimulation/metoclopramide.htm
You might have already found this, but this article is the most in depth that I know of on stasis, including discussion of treatments and the recovery process:
http://www.bio.miami.edu/hare/ileus.html
The article says “It may take several days before any fecal pellets are seen, and it may take two weeks or more of motility therapy before the intestine is moving normally again. We know of one case in which a rabbit produced no fecal pellets for 14 days, but finally did respond to gentle, consistent administration of the above treatment regimen. Patience and persistence are key.”
So don’t give up!
. . . The answers provided in this discussion are for general guideline purposes only. The information is not intended to diagnose or treat your pet. Seek the advice of your veterinarian or a qualified behaviorist.
Thank you so much for your reply! I do not have a rectal thermometer and we’re in the middle of a snowstorm so I’m not able to acquire one. We’ve been very good about keeping him warm, and one of his favorite nap spots is laying on a heating vent, so he’s been doing that whenever he leaves his cage. I’ll be leaving a warm bottle wrapped in a towel for him tonight.
Per the article on Cisapride, I was never told by my vet it needed to be taken before a meal, I’ve been giving it to him after feeding him critical care. I’m wondering if that has anything to do with it?
His ‘diarrhea’ looks nothing like any of the pictures in the page you linked, and it smells strongly of urine. The brownish color is just what’s concerning me, he’s made rust colored pee before in the past but this seems a little darker. There’s two brownish places on his pad that he did overnight, and he’s peed a few times today. No solid material on either of them and they’re still wet. It’s really hard to gauge if its actually diarrhea or not because none of the picture examples I can find of bunny diarrhea look remotely similar.
Through all three of his vet visits she’s noted he’s well hydrated, not losing any weight and staying alert. Today he’s been significantly less alert since introducing the Cisapride, but when I called her earlier today she said the combination of that with the Metaclopromide is going to cause a lot of discomfort.
Also, he’s only on .1 ML of Metacam every 24 hours. I’ve always thought it wasn’t enough, but I’m not going to change his medication doses without being able to consult my vet first. Unfortunately our usual vet is not working on Monday, but we’re still going to take him in to be seen because they have another vet that specializes in exotic pets and see what can be done if his condition is still the same.
Gotcha!
It sounds more like urine.
Completely your call, but I think you could safely split his dose and give 0.05 every 12 hours as the residence time is only about 8 hours for metacam. My vet said this was fine with my bun (they only worry so much about increasing the total amount).
. . . The answers provided in this discussion are for general guideline purposes only. The information is not intended to diagnose or treat your pet. Seek the advice of your veterinarian or a qualified behaviorist.
Just fed him some critical care and water and he really responded well to both. Another family member is taking over for the night to give me some rest since I’ve been at his side 24/7 since Monday. We’re pretty sure the spots are just urine and I overreacted to the color, the spots came overnight and he’s had good/bad hours since. Tummy rubs are helping relieve some gas and he’s acting much more alert after getting more fluids and critical care in his system.
We will venture out to the emergency vet about an hour away if his condition at all worsens overnight, but otherwise he’ll be at the vet first thing Monday morning for a quick checkup with a different vet and get a second professional opinion on his x-ray (I’ll ask for a copy of it to post here as well).
Thank you so much for all your responses DanaM, feeling a lot more optimistic reading your posts and other threads I’ve found on this forum.
Glad he’s responding well!
This part of the last article I shared does stand out to me in your case:
“V. The Road to Recovery: Reduce Stress. (“If it ain’t broke, don’t fix it.”)
It is essential that the caretaker faced with a rabbit in GI stasis be patient, allowing the treatments and medications to work. Rabbits are easily stressed, and excessive handling should be avoided. It may take several days before any fecal pellets are seen, and it may take two weeks or more of motility therapy before the intestine is moving normally again. We know of one case in which a rabbit produced no fecal pellets for 14 days, but finally did respond to gentle, consistent administration of the above treatment regimen. Patience and persistence are key.
Do not make more trips to the veterinarian’s office with the rabbit than absolutely necessary (the stress of travel can slow recovery), but DO contact your veterinarian frequently to report on progress and any changes. Whenever possible, administer medications at home, where the rabbit feels safe and secure.
While you are treating your sick bunny, NEVER separate him/her from his/her bonded partner(s). The stress of separation itself can make the problem worse. We have known bunnies who seemed at death’s door to recover when they were provided with the love and constant attention of their bonded mate. If your bunny does not have a mate, it is even more important that you, his best friend, show him a great deal of calm attention and affection during his ordeal. Rabbits seem to understand when they are being fussed over, and it may help them recover more quickly to know that they are not being abandoned in their misery. But do this within reason. Many a rabbit can sense a caregiver’s fear for his safety, and this in itself can cause stress. Visit and love your bunny, but also give him time to himself to recover.
Every bunny parent should have a stethoscope (not necessarily an expensive one) to monitor intestinal sounds. The gradual return of gentle gurgling is a very good sign: once this begins, the rabbit is on the road to recovery, even if fecal pellets don’t begin pouring out the chute. Administration of intestinal motility agents, gentle massage and supportive care as recounted above should be continued, and gradually tapered as fecal pellets slowly begin to come through the system.
Do not be alarmed if the first batch of fecal pellets is small, hard and misshapen, and even accompanied by some mucus. This is to be expected. Also do not be surprised if the rabbit produces a small bunch of pellets, nothing for a day, and then a bit more. The intestine sometimes seems to regain its function in fits and starts, rather than all at once. Consistent, gentle nursing and reduction of stress are essential at this time.
PLEASE RESIST THE TEMPTATION TO FORCE ADDITIONAL, AGGRESSIVE TREATMENT ONCE THE RABBIT BEGINS TO RECOVER. RECOVERY FROM GI STASIS IS SOMETIMES MADDENINGLY GRADUAL. [We know of one instance in which a rabbit was starting to produce fecal pellets and showing signs of recovery, but the veterinarian overseeing the case insisted on anesthetizing the rabbit to perform oral gavage, enemas with an extension tube and vigorous abdominal massage. Despite advice to the contrary, this veterinarian believed that the mass in the stomach could not possibly pass without such treatment. Tragically, the rabbit died. Necropsy revealed a ruptured liver. We cannot help but wonder whether excessive handling and the unnecessarily aggressive treatments contributed to, or even caused this rabbit’s demise.]”
It sounds like you are taking great care of him, and your vet does sound like she knows what she’s doing. So keep up the good work, and glad you are going to get some rest! Taking care of a sick bun is so stressful and exhausting.
Come on Watson, give us some poops!
. . . The answers provided in this discussion are for general guideline purposes only. The information is not intended to diagnose or treat your pet. Seek the advice of your veterinarian or a qualified behaviorist.
Today has been more of the same. He missed his Sulfatrim on accident so he was feeling bloated, but an hour after and some critical care his tummy is feeling a lot less tense and he’s responding well to rubbing his belly. We’re calling the vet in the morning and seeing if the other vet can see him to check up/get a second opinion. He’s drinking water on his own out of a bowl again, but we’re still using a syringe to get extra hydration and he drinks out of the syringe like its his bottle, but getting his medicine and critical care is trial and error.
His chin is really messy from all the critical care, is there a good way to clean this? It seems to be irritating him a lot.
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