Hmm, is she only peeing on the bed? Or other places too?
Since she’s spayed and this was an abrupt change from her normal behavior, it makes me think she might have a UTI or some other medical issue? Sometimes when bunnies are ill they only have one symptom, so any change in behavior could indicate a health problem.
I will say that many bunnies pee on beds because they are soft and they smell strongly of humans… I would try first blocking access to the bed and see if she’s still having accidents. If she really is only peeing on the bed it is likely marking. One member here put a shower curtain on the bed, with a blanket over it, which blocked the smell of human a bit, and also protected from accidents.
The other thing that can help is to try to have her take “potty breaks” when she is out playing to make sure she uses her box. You can guide her to her box but not lock her in the hutch.
Do you tend to lock her in whenever she goes in? She could be afraid to return to her hutch for fear of not being let out again.
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The answers provided in this discussion are for general guideline purposes only. The information is not intended to diagnose or treat your pet. Seek the advice of your veterinarian or a qualified behaviorist.