I actually have to give Bombur Benadryl during the spring and fall for allergies! Does your bun like carrots? I found that both of my boys will gladly take the medicine if a slice up a baby carrot and squirt a little on each slice. Another trick I’ve used is to squirt in on their greens. Like right now Bombur is on an antibiotic, so in the morning he gets a cut up baby carrot with the meds squirt on top, and at night I drizzle it over his greens. He still eats it all up.

Also, I know I’ve seen Wick talk about it on other posts, but some URIs take a while to run their course with antibiotics so they might have to stay on it for like 6 weeks or longer. I actually think he was on his for a while. Just something to also consider.

I think quite a few of us have mixed yucky meds with sth good. I think it’d be fine to mix an antihistamine with for example banana. I take antihistamines for allergies myself and there’s no restrictions as to what food it can be combined with. (Some antibiotics shouldn’t be mixed with dairy for example -not much of an issue with rabbits though because they shouldn’t eat dairy anyway).

I know forum leader LBJ10 has given cherry flavored children’s Benadryl to one of her buns on her vet’s orders. But I don’t know if her bun hated it.

A&B is correct that some antibiotics will take longer to alleviate symptoms because of how much the infection has invaded the body. Another item to note is that while one antibiotic is not effective, another one could be. If only one was tried, I would ask about trying another one if the symptoms worsen or become too chronic after lessening potential allergens. Worst case scenario, the URI is getting stronger because it’s not getting treated. Different antibiotics will work on different infection types. Going into Wick’s URI treatment, Wick’s vet flat-out said it’s a trial and error to see which will work, but usually it’s successful in one or two medication tries. The first medication was Bactrim for 2 weeks, with no effect. After that, we tried Baytril, which did minimize the symptoms, so we kept at it. Fast forward about a month, it was weird the symptom relief plateau’d, so Flocillin was added on top of Baytril (did not want to take it away since it was helping minimize symptoms). After one shot of Flocillin; life-changing, miraculous silence and lack of nasal discharge. Dual Baytril and Flocillin treatment was continued until my supply ran out, which was about one week after he stopped sneezing (you should keep going a bit after symptoms stop to ensure all the infection is gone). Wick’s was a particular pesky URI, so his entire treatment experiment/course lasted 3mo, though it typically never lasts that long.

Also, here’s a video I made earlier about how I administer antibiotics to Wick when he’s not having it: http://youtu.be/N12eJ5vdo4w

Wooly didn’t seem to mind the cherry flavoring.

Wick very much liked cherry I believe because his Bactrim was cherry-flavored. When he was switched to gross Baytril, he was distraught.