YEAH! That's great news. I am relieved to hear the meds are working. Well, I may still be baffled about the infection, but I do know for sure that antibiotics can cause that reddish/orange color you are seeing. Totally normal. Harmless.
Regarding not spot cleaning her anymore. Is she cleaning herself up well enough? Not like she has to be immaculate, but if she has poopybutt, and didn't or couldn't clean herself, then if left there for days, it can cause soreness, and actually a urinary tract infection if left on too long.
But if she's doing okay on her own and keeping herself "up to par" then should be okay.
Regarding friends and family not understanding. I think people in general who don't know much about rabbits don't understand two things.
1st: A sick rabbit is serious. One minute they can be fine, happy, eating, jumping, and the next they are going down hill. So we even worry when things seem okay, but we know there is something else going on. Rabbits being prey animals, they hide their illness, and it's up to us humans to really notice everything - all the subtle differences. So part of that may seem anal, or worrywartish to some. But really keeping an eye on things isthe only way to tell if a rabbit is hiding something that may need vet treatment. And then some of the most serious problems a rabbit can have are digestive related. A bunny whose digestive tract that slows down or stops can die within 24 hours. I don't think family and friends completely know about how serious a rabbit being sick can be.
2nd . I think many people's image of a rabbit is just a cute fuzzy animal without much personality. So they don't know how you can actually bond with rabbit like you would a dog or some other more vocal or openly expressive animal. I always tell them, you give them room to explore, love and attention, and once they feel safe you will see "who" your bunny is. They do have personalities, and they do communicate, you just have to read their body language - they are talking and expressing all the time.
Well I'm off my soap box now, I'm just happy things are better for Sophie, and maybe soon you can take a sigh of relief as well. Whoohoooo!